Models of sequence evolution

Readings due before class

Required

Amino Acids

Smart Biology - Protein Structure

Recommended Reading

• Junk DNA This is a reply by Ford Doolittle (Dalhousie University in Halifax, a famous evolutionary biologist) to a debate in the mid-10’s about the fundamental nature of junk DNA.

• BLOSUM matrices

• The Life History of 21 Breast Cancers

Action items

• Assignment #4

• Project